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Scientists

  1. Ethical Science News

  2. Jan 22, 2020
Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Accurately Model Gut Function

Researchers at Boston University developed a directed differentiation protocol to produce induced pluripotent stem cells (iPSC)-derived mesenchyme-free human intestinal organoids (HIOs) and used them to create cystic fibrosis patient-derived iPSC-derived organoids for the study of disease-causing mechanisms.