Skip to main content
  1. Health and Nutrition News

  2. Apr 14, 2023

Statins May Contribute to Diabetes Risk

Statins, drugs which are used to lower cholesterol, appear to contribute to diabetes risk, according to a review paper published in the European Journal of Pharmacology.1 The authors analyzed 67 studies representing over 25,000 individuals and found that statins negatively impacted blood sugar control. This happened regardless of the dose and whether or not a person had normal or altered glycemic control. Rosuvastatin and atorvastatin had the worst effect. This is consistent with previous research that has shown that statin therapy worsens glycemic control2 and increases the risk of developing diabetes.3 

Both cardiovascular disease and high cholesterol levels are lifestyle-related diseases that can be prevented and even reversed by a whole food, plant-based diet.  


  1. Alvarez-Jimenez L, Morales-Palomo F, Moreno-Cabañas A, et al. Effects of statin therapy on glycemic control and insulin resistance: a systematic review and meta-analysis. Eur J Pharmacol. 2023;947:175672. doi:10.1016/j.ejphar.2023.175672
  2. Cai R, Yuan Y, Sun J, et al. Statins worsen glycemic control of T2DM in target LDL-c level and LDL-c reduction dependent manners: a meta-analysis. Expert Opin Pharmacother. 2016;17(14):1839-1849. doi:10.1080/14656566.2016.1220539 
  3. Thakker D, Nair S, Pagada A, et al. Statin use and the risk of developing diabetes: a network meta-analysis. Pharmacoepidemiol and Drug Saf. 2016;25(10):1131-1149. doi:10.1002/pds.4020 

More on Diabetes

Interested in this topic?

Learn more and earn free CME credits on!