Semaglutide Associated With Increased Risk of Suicidal Thoughts

World Health Organization data have called attention to a disproportionately high rate of suicidal thoughts among those taking semaglutide, the weight-loss drug marketed as Wegovy and Ozempic. Those on the medication experienced a 45% increased risk of suicidal thoughts; people who were also on antidepressants saw a 445% increased risk. While the absolute risk of suicidal thoughts on semaglutide is still low, further investigation is warranted.