Fallacies of Mice Experiments
De Schutter E. Neuroinformatics. 2019. https://doi.org/10.1007/s12021-019-09420-3 A commentary that calls for experimental neuroscientists to more rigorously justify the necessity and relevance of their work; demonstrates that experimental neuroscience studies using mice are not held to the same rigorous standards as human studies.
Park SE, Georgescu A, Huh D. Science. 2019. doi: 10.1126/science.aaw7894 A review of organ-on-a-chip technology as a platform to study biomedicine and examines how it may be leveraged to address major technical challenges in organoid research. This article discusses emerging opportunities and future hurdles for the development and application of organoid-on-a-chip technology.
Rebooting Human Immunology
Davis MM, Brodin P. Annual Review of Immunology. 2018. https://doi.org/10.1146/annurev-immunol-042617-053206 A review of the recent progress in conceptual and technological approaches to the field of human immunology. This paper proposes this progress is critical for the clinical relevance and discovery of new genetic and environmental influences on the immune system that are not seen in mice.