cholesterol

The Physicians Committee
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cholesterol

Mathematical Modeling Reveals How Cholesterol Promotes Alzheimer’s Disease

Although cholesterol has long been implicated in the pathogenesis of Alzheimer’s disease, the mechanism by which this occurs has not been well understood. Using mathematical modeling, researchers discovered that the cholesterol in cell membranes can accelerate the aggregation of the protein amyloid-β42, a key pathological hallmark in Alzheimer’s disease. 

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