A High-Fat Diet Increases Risk of Breast Cancer

The Physicians Committee

A High-Fat Diet Increases Risk of Breast Cancer

April 15, 2014

Women who eat diets high in fat and saturated fat increase their risk of developing breast cancer, according to a study published by the National Cancer Institute.

Researchers looked at breast cancer subtypes defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 receptor (HER2) using data collected from the European Prospective Investigation into Cancer and Nutrition-Oxford (EPIC) study.

Diet records from 337,327 women over a period of 11.5 years were analyzed for fat content. The women who consumed the most fat had a 20 percent increased risk for ER-positive and PR-positive breast cancer subtypes, and women consuming the most saturated fat faced a 28 percent increased risk for the same breast cancer subtypes, compared with those who consumed the least. Risk of developing HER2-negative breast cancer was 20 percent higher among women consuming the most saturated fat.

Sieri S, Chiodini P, Agnoli C, et al. Dietary Fat Intake and Development of Specific Breast Cancer Subtypes. J Natl Cancer Inst. Published online April 9, 2014.

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