Value of Tight Glycemic Control in Type 2 Diabetes Questioned

The Physicians Committee

Value of Tight Glycemic Control in Type 2 Diabetes Questioned

November 17, 2016

Tight glycemic control may not be the most effective method for diabetes management, according to a review published in Circulation: Cardiovascular Quality and Outcomes. Researchers from the Mayo Clinic reviewed meta-analyses, position papers, guidelines, and other publications on glycemic control and diabetes complications over the last decade to assess current recommendations. The majority of the literature endorsed tight glycemic control, mostly achieved through medications, as a primary method for diabetes management, despite little or no impact on health outcomes such as neuropathy, blindness, renal disease, or death from heart disease. These findings highlight the limitations with some pharmaceutical interventions for people with type 2 diabetes and call into question the recommendations for tight glycemic control.

Rodríguez-Gutiérrez M, Montori VM. Glycemic control for patients with type 2 diabetes mellitus: our evolving faith in the face of the evidence. Circ Cardiovasc Qual Outcomes. 2016;9:504-512.

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