The National Institutes of Health (NIH) recently awarded 13 investigators around the country two-year grants totaling about $15 million per year to further develop tissue chips to model certain human diseases.
Researchers recently advanced organ-on-chip technology to a new level by adding electrodes to continuously monitor the health, electric activities, and differentiation status of living heart cells in real time.
Using stem cells derived from healthy donors and patients with Hutchinson-Gilford progeria syndrome (a rare disease characterized by premature aging of the blood vessels and heart attacks in childhood), researchers created a new miniature device to mimic the stretching and straining that occurs in the smooth muscle cells of blood vessels during blood flow.
Despite the fact that the dangers of smoking cigarettes to humans are largely not seen in animals, hundreds of thousands of animals have been used in smoking experiments in the past several decades. Now, technology paving the way for a new approach.