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The Physicians Committee



BREAKING RESEARCH NEWS June 3, 2014

Human Cell Culture Can Predict Potential Toxicity of Drugs and Other Chemicals

June 3, 2014

in-vitro-testing

Primary human cells can be used in place of animals to test environmental and industrial chemicals, according to a new paper published in Nature Biotechnology.

Several different human cell types, cultured alone or in combination, were used to test more than 100 drugs that had failed clinical trials and more than 700 chemicals.

This in vitro technique shows promise as an alternative to animal tests for predicting safety issues related to drugs and chemicals to which humans may eventually be exposed.

Kleinstreuer NC, Yang  J, Berg EL, et. al. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nat Biotechnol. Published ahead of print May 18, 2014.
 

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Improving Chemical Safety Without Animals

Ellen DeGeneres Speaks Out Against Taiwanese Rabies Testing

New Scientific Paper Documents Decades of Failure in the Use of Live Animals for Alzheimer’s Disease Research


2014 Archive

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