
The Latest In . . .
By Kristine Kieswer
High Cholesterol and Suicide
The first study of its kind has linked high serum cholesterol levels
with violent suicide. Researchers found a two-fold increase in deaths by firearms,
explosives, hanging, cutting, and other extreme measures, comparing subjects with the
highest and lowest serum cholesterol concentrations. During this century, the Western
world has seen increasing rates of depressionone of the strongest risk factors for
suicidewhich may be caused in part by greater consumption of saturated fatty acids
and lower intake of polyunsaturated fatty acids.
Cholesterol, made naturally by the liver, holds together cell membranes and is
the raw material that builds hormones. A diet that includes cholesterol and saturated fat
from animal products can quickly put cholesterol levels in the danger zone. In contrast,
plant foods contain no cholesterol and little saturated fat, allowing the body to maintain
its own healthy balance.
Past studies have shown that men who have more sex-hormone binding globulin
(SHBG) in their blood are less domineering and aggressive. SHBG is boosted by a diet rich
in plant foods and guards against testosterone's negative effects by holding it at bay
until it is needed by the body.
Tanskanen A, Vartiainen E, Tuomilehto J, et al. High serum cholesterol
and risk of suicide. Am J Psychiatry 2000;157:648-50.
© 2001, PHOTODISC
Hormones Do Not Halt Alzheimer's
Disease...But Vegan Foods May
Researchers randomly assigned 120 patients with mild to moderate Alzheimer's
disease to take low-dose estrogen, high-dose estrogen, or a placebo for 12 months. There
was no significant difference in functional and cognitive outcomes in those who received
ERT and those who did not.
However, at the World Alzheimer's Congress 2000 in Washington, D.C., two reports
showed promise that fruits and vegetables protect against the disease. Researchers
observed the dietary habits of nearly 8,000 men and women free of dementia upon enrolling
in the study. When re-examined six years later, those who ate foods rich in vitamins E and
C were less likely to have developed Alzheimer's disease.
Mulnard RA, Cotman CW, Kawas C, et al. Estrogen replacement therapy for
treatment of mild to moderate Alzheimer's disease: a randomized controlled trial.
Alzheimer's Disease Cooperative Study. JAMA 2000;283:1007-15.
Better Cardiovascular Health Prevents
Dementia
Reducing high blood pressure, losing excess body weight, and keeping cholesterol
levels under control are fundamental keys for good health. A new study has shown these
steps may also help prevent dementia.
Researchers found that overweight men with high blood pressure and high
cholesterol in their 50s were more likely to develop dementia (related to blood vessel
disease) in their late 70s. Vascular dementia is characterized by memory loss and other
declines in mental function. The findings add another important reason to eat a healthy
diet and get regular exercise.
Kalmijn S, Curb JD, Rodriguez BL, Yano K, Abbott RD. The association of
body weight and anthropometry with mortality in elderly men: the Honolulu Heart Program.
Int J Obes Relat Metab Disord 1999;23:395-402. Presented at the American
Academy of Neurology's 52nd Annual Meeting in San Diego.
ALTERNATIVES
TO
ANIMAL EXPERIMENTATION |
Artificial Gut
Agricultural Research Service scientist Raymond Glahn has invented an
"artificial gut" that promises to improve our understanding of iron availability
in foods and supplements. Compared to similar tests performed on rats, the new method is
less expensive, takes just three days instead of ten, is more relevant to humans, and
spares animals' lives.
Scientists hope to use the device to identify foods with the highest iron
absorption to assist developing countries where iron deficiency is still common.
Clogged Arteries Form Early in Life
If you think heart disease only happens to grandparents,
think again. Autopsies performed on men aged 30 to 34 who died in accidents revealed that
20 percent of them had arteries with advanced plaques, the kind that can cause heart
attack or stroke. Researchers looked at 760 coronary arteries and found advanced plaques
in men as young as 15 and in women aged 30 to 34.
"We need to make sure our children are eating healthy foods, exercising,
and not smoking," says Dr. Arthur Zeike, who worked on the study. Not surprisingly,
people who were obese or who had high cholesterol were 2.5 times more likely to have
advanced plaques. A diet rich in whole grains, vegetables, beans, and fruits is free of
artery-clogging cholesterol and low in saturated fat.
McGill HC Jr, McMahan CA, Zieske AW, et al. Association of coronary heart
disease risk factors with microscopic qualities of coronary atherosclerosis in youth.
Circulation 2000;102:374-9.
© 2001, ARTVILLE
Active Women Have Lowered Risk
for Stroke
Women who engage in moderate exercise, including walking, can reduce their risk
of having a stroke, according to a new Harvard study. As part of the Nurses' Health Study,
72,488 female nurses aged 40 to 65 were followed from 1986, completing detailed physical
activity questionnaires three times during the study. The most physically active women had
only half the stroke risk of the least active ones. Exercise helps prevent ischemic
strokes, caused by blockages in the arteries leading to the brain.
Playing sports, going to the gym, or simply walkingall proved effective
for reducing risk. Of course, the longer and brisker the walks, the more protection they
provided. This study showed that for every hour spent in moderate to vigorous physical
activity each week, stroke risk was cut by roughly 10 percenteven for those women
who had previously been inactive. Eating a diet rich in fruits and vegetables, not
smoking, and maintaining a healthy body weight reduce stroke risk as well.
Hu F, Stampfer M, Colditz G, et al. Physical activity and risk of stroke
in women. JAMA 2000;283:2961-7.
Dairy and Crohn's Disease
The dairy industry is again battling Johne's (pronounced yo-nees)
disease, caused by a bacterium that interferes with digestion, lowers milk production, and
eventually kills infected cows. But they are worried about more than lost profits.
Research has linked the disease to the human intestinal disorder Crohn's disease. Earlier
this year, Oregon State University and the USDA implemented a plan to carefully screen
cow's blood and fecal samples for the bacteria, but this won't provide protection for
average consumers.
Crohn's disease is a type of inflammation in the digestive tract. It often
affects young people, causing fever, diarrhea, and pain after eating, sometimes leading to
serious complications. In addition to genetic factors and bacterial infections, Crohn's
disease is affected by diet. Many people with the illness have little
fiberspecifically vegetables and fruitsand too much sugar in their diet.
Boosting plant foods, including whole grain bread and brown rice, while avoiding sugar,
white flour, and white rice has reduced patient hospitalizations in research studies.
Daily Exercise, Not Calcium, Is Key to
Strong Bones
A long-term study of women found that bone density was significantly affected by
how much exercise they got in their teen years, the time when girls develop 40 to 50
percent of their skeletal mass, while calcium intake made no difference.
Researchers at Penn State focused on hipbone density, a common site for
fractures in women with osteoporosis. For six years, beginning at age 12, 81 girls were
evaluated for dietary habits, sports activities, and participated in a calcium
supplementation study. Consistent with past studies, intake of calcium above 900
milligrams per day (two glasses of milk) had no lasting effect on bone strength. Regular
exercise did.
Lloyd T, Chinchilli VM, Johnson-Rollings N, Kieselhorst K, Eggli DF,
Marcus R. Adult female hipbone density reflects teenage sports-exercise patterns but not
teenage calcium intake. Pediatrics 2000;106:40-4. |