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The Physicians Committee



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BREAKING MEDICAL NEWS April 22, 2002

Anger and Heart Disease

April 22, 2002

Men who rate themselves as generally angry on questionnaires given early in life are, by the age of 55, three times more likely to have heart disease and six times more likely to have a heart attack (myocardial infarction), compared to other men. The Johns Hopkins University study appears in today's Archives of Internal Medicine.

Chang PP, Ford DE, Meoni LA, Wang NY, Klag MJ. Anger in young men and subsequent premature cardiovascular disease. Arch Intern Med. 2002;162:901-906.

Ford DE, Mead LA, Chang PP, Cooper-Patrick L, Wang NY, Klag MJ. Depression is a risk factor for coronary artery disease in men: the precursors study. Arch Intern Med. 1998;158:1422-1426.

One common theme between anger and heart disease: Testosterone may lead to aggressiveness, and men with low levels of sex-hormone binding globulin (SHBG), which binds testosterone, tend to be rated by their wives as more domineering and difficult to get along with, compared to men with higher SHBG levels. Low-fat, vegan diets lower cholesterol levels, but also raise SHBG, helping to mute testosterone effects.

Gray A, Jackson DN, McKinlay JB. The relation between dominance, anger, and hormones in normally aging men: results from the Massachusetts Male Aging Study. Psychosomatic Medicine. 1991;53:375-385.

Barnard ND, Scialli AR, Hurlock D, Bertron P. Diet and sex-hormone binding globulin, dysmenorrhea, and premenstrual symptoms. Obstet Gynecol. 2000;95:245-250.

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Breaking Medical News is a service of the Physicians Committee for Responsible Medicine, 5100 Wisconsin Ave., Ste. 400, Washington, DC 20016, 202-686-2210. Join the Physicians Committee and receive the quarterly magazine, Good Medicine.



   
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